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Pierangelo Geppetti Selected Research

ibuprofen acyl glucuronide

1/2019The acyl-glucuronide metabolite of ibuprofen has analgesic and anti-inflammatory effects via the TRPA1 channel.

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Pierangelo Geppetti Research Topics

Disease

42Pain (Aches)
01/2022 - 11/2006
39Migraine Disorders (Migraine)
04/2022 - 04/2005
26Hyperalgesia
07/2022 - 05/2004
20Inflammation (Inflammations)
01/2020 - 11/2002
15Neurogenic Inflammation
12/2014 - 04/2004
13Headache (Headaches)
01/2022 - 02/2012
12Melanoma (Melanoma, Malignant)
11/2021 - 06/2005
12Neuralgia (Stump Neuralgia)
12/2019 - 10/2010
10Neoplasms (Cancer)
01/2021 - 02/2006
8Asthma (Bronchial Asthma)
04/2014 - 01/2002
7Hypersensitivity (Allergy)
01/2020 - 08/2007
7Chronic Obstructive Pulmonary Disease (COPD)
04/2014 - 01/2003
6Cough
06/2015 - 08/2006
4Cancer Pain
01/2022 - 01/2019
4Cold Hypersensitivity
12/2020 - 07/2011
3Prescription Drug Overuse
01/2022 - 11/2018
3Pigmented Nevus (Melanocytic Nevus)
11/2021 - 06/2005
3Ischemia
01/2020 - 08/2002
3Pruritus (Itching)
12/2014 - 04/2013
3Edema (Dropsy)
07/2014 - 12/2010
3Peripheral Nervous System Diseases (PNS Diseases)
05/2013 - 09/2006
2Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
01/2022 - 08/2021
2Dysplastic Nevus Syndrome (Dysplastic Nevus)
11/2021 - 02/2006
2Carcinogenesis
11/2021 - 09/2006
2Breast Neoplasms (Breast Cancer)
11/2021 - 12/2014
2Pneumonia (Pneumonitis)
11/2021 - 11/2007
2COVID-19
11/2021 - 10/2020
2Secondary Headache Disorders
03/2021 - 12/2015
2Neuroinflammatory Diseases
01/2020 - 12/2017
2Epilepsy (Aura)
11/2018 - 01/2018
2Gout
07/2014 - 11/2013

Drug/Important Bio-Agent (IBA)

34AnkyrinsIBA
01/2022 - 01/2010
20Calcitonin Gene-Related PeptideIBA
04/2022 - 05/2004
17TRPA1 Cation ChannelIBA
11/2021 - 08/2008
12Pharmaceutical PreparationsIBA
05/2021 - 02/2006
10NeuropeptidesIBA
01/2022 - 01/2003
10Capsaicin (Zostrix)FDA Link
11/2017 - 04/2004
9Ion Channels (Ion Channel)IBA
01/2022 - 02/2007
8Peptides (Polypeptides)IBA
02/2019 - 08/2002
8Irritants (Vesicants)IBA
05/2014 - 08/2006
72- (1,3- dimethyl- 2,6- dioxo- 1,2,3,6- tetrahydro- 7H- purin- 7- yl)- N- (4- isopropylphenyl)acetamideIBA
01/2019 - 07/2011
7Substance PIBA
01/2017 - 05/2004
6Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
11/2021 - 11/2013
6salicylhydroxamic acid (SHAM)IBA
01/2019 - 01/2016
5Analgesics (Analgesic Drugs)IBA
01/2022 - 07/2007
5Monoclonal AntibodiesIBA
01/2022 - 01/2019
54-hydroxy-2-nonenal (4-hydroxynonenal)IBA
11/2021 - 08/2007
5Reactive Oxygen Species (Oxygen Radicals)IBA
11/2021 - 08/2007
5AntioxidantsIBA
12/2020 - 04/2012
5Type A Botulinum Toxins (Botox)FDA Link
12/2020 - 07/2007
5Adrenergic Receptors (Adrenergic Receptor)IBA
01/2020 - 04/2011
5Peptide Hydrolases (Proteases)FDA Link
06/2009 - 08/2002
5TRPV Cation ChannelsIBA
11/2006 - 04/2004
4Thioctic Acid (Lipoic Acid)IBA
01/2020 - 05/2013
4Ethanol (Ethyl Alcohol)IBA
12/2019 - 06/2004
4Calcitonin Gene-Related Peptide Receptors (Calcitonin-Gene Related Peptide Receptor)IBA
01/2019 - 02/2009
4CationsIBA
01/2019 - 05/2004
4SmokeIBA
02/2012 - 11/2007
4Acrolein (Aqualin)IBA
01/2012 - 08/2007
4PAR-2 ReceptorIBA
02/2007 - 11/2002
3AntibodiesIBA
01/2022 - 09/2006
3galcanezumabIBA
01/2022 - 01/2022
3CalciumIBA
11/2021 - 01/2002
3Propranolol (Inderal)FDA LinkGeneric
01/2020 - 01/2018
3AcetaldehydeIBA
12/2019 - 06/2004
3Dinoprostone (PGE2)FDA Link
02/2019 - 07/2015
3Pain-FreeIBA
11/2018 - 01/2018
3Formaldehyde (Formol)FDA Link
11/2017 - 02/2012
3Bortezomib (Velcade)FDA Link
01/2017 - 05/2013
3Proteins (Proteins, Gene)FDA Link
11/2015 - 06/2005
3TachykininsIBA
01/2014 - 10/2005
3Oxaliplatin (Eloxatin)FDA LinkGeneric
05/2013 - 07/2011
3resiniferatoxinIBA
02/2009 - 02/2005
3Calcitonin Gene-Related Peptide Receptor AntagonistsIBA
02/2009 - 04/2005
3AldehydesIBA
07/2008 - 08/2007
3TrypsinIBA
08/2006 - 08/2002
3Tryptases (Tryptase)IBA
10/2005 - 11/2002
2AcetoneIBA
07/2022 - 10/2010
2fremanezumabIBA
01/2022 - 11/2021
2Tryptamines (Triptans)IBA
01/2022 - 10/2010
2erenumabIBA
01/2022 - 01/2022
2Acetaminophen (Paracetamol)FDA LinkGeneric
05/2021 - 12/2010
2Methadone (Dolophine)FDA LinkGeneric
03/2021 - 12/2015
2NADP (NADPH)IBA
12/2019 - 01/2016
2CarrageenanIBA
01/2019 - 07/2015
2capsazepineIBA
01/2019 - 08/2006
2Calcium Channels (Calcium Channel)IBA
01/2019 - 11/2016
2Norepinephrine (Noradrenaline)FDA LinkGeneric
02/2018 - 01/2015
2Nitric Oxide (Nitrogen Monoxide)FDA Link
01/2018 - 01/2002
2Neurokinin-1 Receptors (Neurokinin 1 Receptor)IBA
01/2017 - 09/2006
2Aromatase InhibitorsIBA
12/2016 - 12/2014
2Interleukin-8 (Interleukin 8)IBA
11/2016 - 11/2007
2Bile Acids and Salts (Bile Acids)IBA
12/2014 - 04/2013
2Antihypertensive Agents (Antihypertensives)IBA
08/2014 - 11/2013
2Uric Acid (Urate)IBA
07/2014 - 11/2013

Therapy/Procedure

12Therapeutics
01/2020 - 06/2006
5Vagus Nerve Stimulation
01/2019 - 01/2018
4Ligation
07/2022 - 10/2010
4Drug Therapy (Chemotherapy)
04/2022 - 05/2013
2Retreatment
01/2022 - 12/2017